Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 20 de 44.880
Filter
1.
Nursing ; 54(5): 38-44, 2024 May 01.
Article in English | MEDLINE | ID: mdl-38640033

ABSTRACT

ABSTRACT: Nurse informaticists (NIs) play a pivotal role in addressing health-related social needs through integrating technology into electronic health records. NIs navigate regulatory landscapes, emphasizing screening for social determinants of health during hospital encounters. This article underscores NIs' strategic contributions to optimizing data collection, supporting health equity, and utilizing innovative technologies to bridge gaps in healthcare outcomes.


Subject(s)
Health Equity , Humans , Nurse's Role , Electronic Health Records , Health Facilities
2.
Br J Community Nurs ; 29(4): 162-170, 2024 Apr 02.
Article in English | MEDLINE | ID: mdl-38564442

ABSTRACT

Home enteral tube feeding (HEF) has many benefits and is largely safe practice. Some complications have historically required intervention in the acute setting, including traumatic displacement of feeding tubes (i.e. internal bumper/balloon removed intact), and evidence to support the safe replacement of these tubes in the community is lacking. To address this, a service enabling community homecare nurses (CHN) to replace traumatically displaced feeding tubes was designed and evaluated. Adult patients presenting with a traumatically displaced feeding tube over 29 months were included in the service evaluation. Baseline characteristics and outcomes at day 1, 7 and 6 months post-replacement were recorded. A total of 71 tube replacements were performed by CHNs in 60 patients. No clinical complications were recorded at any follow-up points. A simple cost analysis estimated savings of £235 754.40. These results suggest that nurse-led replacement of traumatically displaced feeding tubes in adults in the community is low-risk and offers potential cost savings.


Subject(s)
Gastrostomy , Nurses , Adult , Humans , Nurse's Role , Enteral Nutrition/methods , Intubation, Gastrointestinal
3.
J Palliat Med ; 27(4): 579-580, 2024 Apr.
Article in English | MEDLINE | ID: mdl-38574338
4.
Health Sociol Rev ; 33(1): 10-23, 2024 Mar.
Article in English | MEDLINE | ID: mdl-38557328

ABSTRACT

This paper examines the conflicting temporal orders of the regional nurse, a role which has been introduced to deal with the increasing demands of aged care and workforce shortages in regional settings. We build on ethnographic research in the Netherlands, in which we examine regional district nurses as a new professional role that attends to (sub)acute care needs, connecting and coordinating different places of care during out of office hours. We use the concept of 'temporal regional order' to reflect on the different ways caring practices are temporally structured by management and care practitioners, in close interaction with patients and informal care givers. In the results three types of disruptions of the regional temporal order are distinguished: interfering bodily rhythms and needs; (un)expected workings of technologies; and disrupting acts of patient and relatives. It was region nurses' prime responsibility to stabilise these interferences and prevent or soften a disruption of the regional order. In accomplishing this, we show how nurses craft their professional role in between various care settings, without getting involved too much in patient care, to be mobile as 'temporal caregivers'.


Subject(s)
Nurse's Role , Humans , Netherlands , Aged , Anthropology, Cultural , Geriatric Nursing
5.
J Prof Nurs ; 51: 101-108, 2024.
Article in English | MEDLINE | ID: mdl-38614667

ABSTRACT

BACKGROUND: Increasingly, registered nurses (RNs) are incorporated into ambulatory care teams. Yet, limited research exists on the roles of RNs across these settings. PURPOSE: The purpose of this study was to examine the roles performed by RNs (and their senior BSN students) in primary care and public health settings. METHODS: Working with nine RN preceptors, 15 students tracked all patient visits during a 150-h immersion experience using the Typhon™ clinical-tracking software. RESULTS: The BSN student/RN dyads conducted 1218 patient visits completing 8536 RN roles in 15 distinct categories. Most patients were African American and female (n = 736; 60.1 %) with an average age of 38.4 (SD 22.12). Patient demographics varied by site. The most common roles performed by the RN/student dyad were health assessment, behavioral health screening, and telehealth. Roles of the RNs and the student level of independence were significantly different across sites (Fisher's Exact test [p < .001]). CONCLUSIONS: Our results argue that RNs are providing substantial value to these FQHC and public heath settings. An academic/practice partnership, including a shared curricular review, can provide a strategic advantage for educators to ensure that health systems realize the unique roles for RNs and educators provide 21st century education.


Subject(s)
Medically Underserved Area , Students , Humans , Female , Adult , Black or African American , Educational Status , Nurse's Role
6.
Rev Lat Am Enfermagem ; 32: e4137, 2024.
Article in English, Spanish, Portuguese | MEDLINE | ID: mdl-38655936

ABSTRACT

OBJECTIVE: to analyze nurses' role in collecting, identifying and preserving traces in Emergency care for victims of violence, from the perspective of these professionals. METHOD: a qualitative study with an exploratory and descriptive approach. It was developed through semi-structured interviews with 21 nurses from hospitals that are part of the intersectoral flow to assist victims of violence from two reference hospitals in this type of care, in a capital city from southern Brazil. Nurses that are members of the multiprofessional team working in the Emergency areas at the respective hospitals were included; in turn, the exclusion criteria corresponded to professionals relocated in Emergency areas during the pandemic. Data analysis was performed according to Thematic Content Analysis. RESULTS: the data were discussed in five categories: 1) Professional qualification; 2) Institutional protocol and materials; 3) The professionals' perceptions; 4) The professionals' actions; and 5) Team structure. CONCLUSION: Nursing professionals' skills in collecting, identifying and preserving traces in Emergency assistance provided to victims of violence need to be better organized, structured and standardized. The presence of Nursing professionals in the care of victims of violence in Emergency services is undeniable, but their importance is still underestimated and their potential contribution to the forensic approach is underused.


Subject(s)
Forensic Nursing , Qualitative Research , Humans , Forensic Nursing/organization & administration , Female , Brazil , Male , Nurse's Role , Adult , Violence , Emergency Medical Services/standards , Emergency Medical Services/organization & administration , Middle Aged , Emergency Service, Hospital , Crime Victims
8.
Cult. cuid ; 28(68): 179-188, Abr 10, 2024. ilus
Article in Spanish | IBECS | ID: ibc-232321

ABSTRACT

Introducción: Maria José Bezerra, Maria Soldado, mujernegra nacida en la ciudad de Limeira, São Paulo, heroína ysímbolo de la Revolución Constitucionalista de 1932, fueuna enfermera de guerra reconocida por su fuerza, valor,patriotismo y abnegación.Objetivo: historiar la trayectoria vital personal y profesionalde Maria José Bezerra. Metodología: Investigación biográficarealizada a partir de registros bibliográficos y documentales.Resultados: Maria José Bezerra sirvió como enfermeramiembro de la Legión Negra en la Guerra Civil de la RevoluciónConstitucionalista de 1932, destacando por sus logros, con unacontribución activa a la construcción de la historia del país.Conclusión: La invisibilidad negra traduce la injusticia, laincoherencia de los derechos y también los actos que tratande deshonrar al individuo en sus aspectos individuales ycolectivos. El estudio de la trayectoria de esta mujer luchadorase constituye como una estrategia para dar voz, fuerza ysentido a hacer pública la historia de una representantede la población negra, y también debería incluirse en loscurrículos académicos.(AU)


Introduction: Maria José Bezerra, a black woman born inthe city of Limeira, São Paulo, hero and symbol of the 1932Constitutionalist Revolution, was a war nurse recognized forher strength, courage, patriotism and abnegation.Objective: To historicize Maria José Bezerra's personal andprofessional life trajectory. Methodology: Biographical research based on bibliographicand documentary records.Results: Maria José Bezerra acted as a nurse member ofthe Black Legion in the Civil War of the ConstitutionalistRevolution of 1932, stood out for her achievements, withactive contribution in the construction of the country's history.Conclusion: Black invisibility translates as injustice, inconsistencyof rights, and even acts that try to discredit the individualin their individual and collective aspects. The study of thetrajectory of this woman fighter constitutes a strategy togive voice, strength and meaning to make public the historyof a representative of the black population, and the themeshould also be included in academic curricula.(AU)


Introdução: Maria José Bezerra, a Maria Soldado, uma mulhernegra nascida na cidade de Limeira, São Paulo, heroína esímbolo da Revolução Constitucionalista de 1932, foi umaenfermeira de guerra reconhecida pela força, coragem,patriotismo e abnegação.Objetivo: Historicizar a trajetória de vida pessoal e profissionalde Maria José Bezerra.Metodologia: Pesquisa biográfica realizada a partir de registrosbibliográficos e documentais.Resultados: Maria José Bezerra atuou como enfermeiramembro da Legião Negra na Guerra Civil da RevoluçãoConstitucionalista de 1932, destacou-se pelos seus feitos,com contribuição ativa na construção da história do país.Conclusão: A invisibilidade negra traduz a injustiça, incoerênciade direitos e, ainda, atos que tentam desabonar o indivíduoem seus aspectos individuais e coletivos. O estudo da trajetóriadessa mulher lutadora constitui-se como estratégia de darvoz, força e sentido de tornar público a história de umarepresentante da população negra, devendo ainda ser inclusaa temática nos currículos acadêmicos.(AU)


Subject(s)
Humans , Female , History of Nursing , Nurse's Role , Military Personnel , Racism , Brazil , Nursing
9.
S Afr Med J ; 114(2): e1306, 2024 Feb 13.
Article in English | MEDLINE | ID: mdl-38525581

ABSTRACT

BACKGROUND: Low- and middle-income countries have a critical shortage of specialist anaesthetists. Most patients arriving for surgery are of low perioperative risk. Without immediate access to preoperative specialist care, an appropriate interim strategy may be to ensure that only high-risk patients are seen preoperatively by a specialist. Matching human resources to the burden of disease with a nurse-administered pre-operative screening tool to identify high-risk patients who might benefit from specialist review prior to the day of surgery may be an effective strategy. OBJECTIVE: To develop a nurse-administered preoperative anaesthesia screening tool to identify patients who would most likely benefit from a specialist review before the day of surgery, and those patients who could safely be seen by the anaesthetist on the day of surgery. This would ensure adequate time for optimisation of high-risk patients preoperatively and limit avoidable day-of-surgery cancellations. METHODS: A systematic review was conducted to identify preoperative screening questions for use in a three-round Delphi consensus process. A panel of 16 experienced full-time clinical anaesthetists representing all university-affiliated anaesthesia departments in South Africa participated to define a nurses' screening tool for preoperative assessment. RESULTS: Ninety-eight studies were identified, which generated 79 questions. An additional 14 items identified by the facilitators were added to create a list of 93 questions for the first round. The final screening tool consisted of 81 questions, of which 37 were deemed critical to identify patients who should be seen by a specialist prior to the day of surgery. CONCLUSION: A structured nurse-administered preoperative screening tool is proposed to identify high-risk patients who are likely to benefit from a timely preoperative specialist anaesthetist review to avoid cancellation on the day of surgery.


Subject(s)
Anesthesia , Nurse's Role , Humans , Delphi Technique , South Africa , Preoperative Care
10.
Clin J Oncol Nurs ; 28(2): 143-147, 2024 Mar 15.
Article in English | MEDLINE | ID: mdl-38511922

ABSTRACT

Patients receiving oncology care are at risk for malnutrition, which is associated with decreased cancer treatment tolerance, lower quality of life, and increased mortality. Implementation of frequent nutritional screening is.


Subject(s)
Malnutrition , Neoplasms , Humans , Nutritional Status , Nutrition Assessment , Quality of Life , Nurse's Role , Malnutrition/diagnosis , Neoplasms/complications , Mass Screening
11.
Int J Qual Stud Health Well-being ; 19(1): 2323060, 2024 Dec.
Article in English | MEDLINE | ID: mdl-38446054

ABSTRACT

PURPOSE: The prevalence of Type 2 diabetes is rapidly increasing, with 537 million people estimated to have diabetes in 2021. The literature suggests that nurses can deliver effective person-centred diabetes care and that families can be essential in supporting patients. Thus, a Nurse-led Family-based (NLFB) approach may be particularly effective. This study aims to explore the perceptions of nurses, adults with type 2 diabetes, and family members regarding the NLFB intervention. METHODS: Guided by the UK Medical Research Council Framework, this seminal study adopted a qualitative, descriptive approach with content analysis. Data were obtained through 16 semi-structured, in-depth interviews. Themes emerged based on an inductive process using constant comparison (Graneheim and Lundman 2004). The COREQ checklist was used in ensuring rigour. RESULTS: Three main themes emerged includes: (1) nurses' experiences with current diabetes care practices, (2) stakeholders' views on the development of a NLFB approach, and (3) merging the nurse-led family aspects into the diabetes care. The key challenges are the dominant medical model, lack of specialist nurses, and time. The key facilitators are knowledge and social support. CONCLUSION: The study recommends stakeholders embrace nursing empowerment strategies and involve families to enhance the nurses' advanced roles and family inclusion in healthcare.


Subject(s)
Diabetes Mellitus, Type 2 , Adult , Humans , Diabetes Mellitus, Type 2/therapy , Nurse's Role , Qualitative Research , Family , Patient-Centered Care
12.
J Vasc Nurs ; 42(1): 35-43, 2024 Mar.
Article in English | MEDLINE | ID: mdl-38555176

ABSTRACT

INTRODUCTION: Screening for cardiovascular disease (CVD) followed by preventive medication is expected to reduce CVD (2,3,5). However, insufficient medication adherence may affect screening effectiveness (11-12). It remains uncertain which interventions are suitable to support citizens in their decision-making about taking CVD preventive medication. OBJECTIVE: We evaluated if and how three nurse-led telephone follow-up (TFU) calls supported citizens in making informed decisions regarding CVD preventive medication and thereby potentially strengthened their medication adherence. METHODS: Employing a theory-based evaluation design inspired by Dahler-Larsen (39-41), we developed and tested a programme theory describing if and how the TFU calls supported medical decision-making and potentially improved medication adherence. Data were collected via telephone. FINDINGS: We analysed 61 TFU calls collected between May 2017 and April 2019 and found that TFU calls supported participants' reflections on preventive medication. TFU calls supported informed decision-making regarding initiating medication, allowing participants to consider personal preferences and values, including both opting for and abstaining from medication. The content of the TFU calls revolved around four crucial themes: I) understanding the purpose of taking the medicine; II) meaningfulness and joint reflection support the decision; III) relation to healthcare professionals; and IV) taking medication for the first time. CONCLUSION: TFU calls effectively supported citizens' understanding and addressed their needs. Trusted healthcare professionals' recommendations were preferred for decisional support. Initiating CVD preventive medication was particularly challenging for citizens who had not previously taken such medication. We recommend scheduling TFU calls early: the first after one week, the second after one month and the third after six months.


Subject(s)
Cardiovascular Diseases , Nurse's Role , Humans , Follow-Up Studies , Telephone , Cardiovascular Diseases/drug therapy , Cardiovascular Diseases/prevention & control , Medication Adherence
13.
Nurse Educ Today ; 137: 106152, 2024 Jun.
Article in English | MEDLINE | ID: mdl-38513303

ABSTRACT

BACKGROUND: Mentorship has been recognized as a strategy to develop leadership competencies in clinical leaders and has been integrated into leadership programs. However, there are few published frameworks to guide mentor conversations with mentees training to assume nursing leadership roles. OBJECTIVE: This study explores mentors' perceptions of 6-month mentorship, a component of the Strengths-Based Nursing Leadership program, the effectiveness of the Facilitated Engagement Approach, a pedagogical strategy developed to facilitate conversation between the mentor and mentee, and the impact of mentorship on leadership practice of mentees. METHODS: A mixed method qualitative and quantitative approach was used with semi-structured interviews and bi-weekly survey among mentors. Data were thematically analyzed. RESULTS: Mentors described the use of the Facilitated Engagement Approach to guide their mentorship conversations and found it to be effective in mentoring program participants. Mentors described techniques used and the process of deepening a reflective mentorship conversation. The Spiraling Process (58 %) and the Story Sharing Process (74 %) were integral aspects of the Facilitated Engagement Approach used. Mentorship was found to be impactful in that mentors reported a change in their mentee. CONCLUSIONS: The Facilitated Engagement Approach was an effective tool for mentees and mentors to develop leadership capacities.


Subject(s)
Mentoring , Mentors , Humans , Program Evaluation , Nurse's Role , Surveys and Questionnaires
14.
Article in English | MEDLINE | ID: mdl-38541359

ABSTRACT

Assuring home care (HC) workers' safety is challenging because the work environment is a private home. This paper presents the process evaluation for a proof-of-concept safety intervention study to assess whether nurse-led safety coaching, using motivational interviewing and a safety handbook, could enable HC clients to improve safety in their homes. The process evaluation objectives were to (i) document the intervention's implementation progress and (ii) assess the intervention's dose delivery, dose reception, and fidelity. Five agencies employing liaisons (n = 5) and nurse managers (NMs, n = 8) implemented this study's intervention and control arms. NMs assigned to the intervention arm (n = 6) coached 34 clients. Process evaluation metrics were assessed with mixed-methods data from (i) surveys completed by NMs during the intervention, (ii) postintervention audio-recorded and transcribed interviews (n = 6) with NMs and liaisons, and (iii) study progress tracking tools. The delivered dose efficiency was 85%, measured by the distribution of safety handbook copies to clients. About 94% of clients (n = 32) were considered "engaged" or "maybe engaged" during the safety coaching. Most coached clients (n = 30) were reachable for follow-up by NMs to assess intervention progress. Despite challenges, the intervention was implemented with good fidelity. Safety coaching can be applied in many HC contexts in larger populations.


Subject(s)
Home Care Services , Mentoring , Humans , Nurse's Role
15.
Transpl Infect Dis ; 26(2): e14268, 2024 Apr.
Article in English | MEDLINE | ID: mdl-38477039

ABSTRACT

BACKGROUND: Prolonged periods of immunosuppression during hematopoietic stem cell transplant (HSCT) can result in serious infectious complications and contribute to transplant-related morbidity and mortality. Adherence to standardized pre and postinfection screening guidelines, prescribed medications, and early identification of infectious symptoms through comprehensive patient and family education are crucial to minimizing infectious complications. Advanced practice nurses (APNs) are key members of the multidisciplinary care team in the HSCT specialty, maintaining a specialized skillset and scope of practice which includes a holistic based, preventative medicine and risk mitigation approach. METHODS: This review sought to describe the role of the APN in HSCT care and to further examine existing APN led models of care which focus on infection prevention and education throughout the HSCT treatment journey. RESULTS: No studies specifically examined the APN role in infectious diseases risk assessment, screening, and management throughout the HSCT journey were identified throughout our review, however, there was considerable evidence to demonstrate the benefits of APN led care in the oncology and solid organ transplantation specialty which led to improvements in continuity of care, overall patient outcomes, and multidisciplinary team collaboration. The key themes identified in our review, were the role of the APN in the delivery of comprehensive patient and family education, the role of the APN in supporting, mentoring, and educating junior medical and nursing teams, the collaboration between the APN and the multidisciplinary care team, and the role of the APN in prompt recognition, triage, and management of treatment related complications, such as infection.


Subject(s)
Hematopoietic Stem Cell Transplantation , Nurse's Role , Humans , Immunosuppression Therapy , Hematopoietic Stem Cell Transplantation/adverse effects
16.
Pediatr Neurol ; 154: 70-78, 2024 May.
Article in English | MEDLINE | ID: mdl-38552337

ABSTRACT

BACKGROUND: This study aimed to evaluate the effects of a nurse-led cognitive behavioral intervention for parents of children with epilepsy (CWE). METHODS: The study recruited 238 CWE from the neurology ward of Xiangya Hospital from March 2019 to August 2022. According to the interventions after discharge, the children and their parents were randomly divided into 117 parent-child dyads in the intervention group and 121 parent-child dyads in the control group. The seizure severity and treatment compliance in CWE as well as the parents' psychological states and satisfaction with the care provided by nurses were compared before and after intervention. RESULTS: The follow-up six months after discharge showed that the seizure frequency among CWE in the intervention group was significantly less than the controls (P = 0.048). Compared with the controls, the intervention group also reported fewer symptoms of anxiety and depression, better sleep quality, and more positive attitudes toward epilepsy, as well as higher nursing satisfaction (P < 0.001). The correlation analysis indicated the correlation of CWE's seizure severity was correlated with the compliance, parents' psychological states, and parents' satisfaction with the care provided by nurses. CONCLUSIONS: The adoption of the nurse-led cognitive behavioral intervention on parents of CWE can improve the parents' mental health status and their satisfaction with the nurses, which can have a positive association with the seizure severity of CWE. In light of this information, this nursing intervention may be a new method for the long-term disease management of CWE.


Subject(s)
Epilepsy , Nurse's Role , Humans , Parents/psychology , Epilepsy/diagnosis , Seizures , Cognition
17.
Appl Nurs Res ; 75: 151764, 2024 Feb.
Article in English | MEDLINE | ID: mdl-38490795

ABSTRACT

AIM: The purpose of this manuscript is to report the findings of a qualitative content analysis of interviews with VA Nurse Scientists about work life experiences, barriers, and facilitators across the enterprise. BACKGROUND: The VA enterprise is widely variable in terms of size, services, research activity, and budget. For this reason, the roles of nurses with a research-focused doctorate are also quite diverse. METHODS: We purposively sampled 18 PhD prepared Nurse Scientists based on a variety geographic locations, titles, and years in the field and who conduct research. We conducted semi-structured interviews over the virtual platform, WebEx. Interviews, averaging 1 h in length, were conducted between April and May 2021. We analyzed interviews using deductive and inductive content analysis. RESULTS: We found five key factors affecting VA Nurse Scientists. Each factor emerged as an important issue influencing whether Nurse Scientists reported being successful, supported, and productive in their research. These include having: 1) mentorship, 2) supportive leadership 3) available resources, 4) respect and understanding from clinical and research colleagues who understand a Nurse Scientist's role in research, and 5) a career pathway. CONCLUSIONS: VA Nurse Scientists are leaders and innovators who generate evidence to improve health outcomes and promote equity in health and health care of Veterans, their families, and caregivers. Results from this project suggest that many Nurse Scientists need additional mentorship, resources, and networks to advance their development, increase their funding success, and maximize the impact of their role, ultimately enhancing care of Veterans and their families.


Subject(s)
Veterans Health , Veterans , Humans , Nurse's Role , Qualitative Research
18.
Nurs Sci Q ; 37(2): 125-133, 2024 Apr.
Article in English | MEDLINE | ID: mdl-38491882

ABSTRACT

Dr. Barbara M. Dossey is an internationally recognized pioneer in the holistic nursing and nurse coaching movements. She is a Florence Nightingale scholar, nurse theorist, and national and international speaker and teacher on the role of holistic, integral, and integrative nursing and nurse coaching in the integrative healthcare paradigm. Her theory of integral nursing presents the science and art of nursing. Her coauthored theory of integrative nurse coaching, a middle-range theory, is a framework to guide integrative nurse coaches in nurse coaching practice, education, research, and healthcare policy. In this column, Dr. Dossey shares her scholarly journey of joy.


Subject(s)
Holistic Nursing , Mentoring , Humans , Female , Nurse's Role
19.
BMJ Open ; 14(3): e084412, 2024 Mar 23.
Article in English | MEDLINE | ID: mdl-38521521

ABSTRACT

INTRODUCTION: Androgen deprivation therapy (ADT) is commonly used to treat men with locally advanced or metastatic prostate cancer. Men receiving ADT experience numerous side effects and frequently report unmet supportive care needs. An essential part of quality cancer care is survivorship care. To date, an optimal effective approach to survivorship care for men with prostate cancer on ADT has not been described. This protocol describes a randomised trial of tele-based nurse-led survivorship that addresses this knowledge gap: (1) determine the effectiveness of a nurse-led survivorship care intervention (PCEssentials), relative to usual care, for improving health-related quality of life (HR-QoL) in men with prostate cancer undergoing ADT and (2) evaluate PCEssentials implementation strategies and outcomes, including cost-effectiveness, compared with usual care. METHODS AND ANALYSIS: This is an effectiveness-implementation hybrid (type 1) trial with participants randomised to one of two arms: (1) minimally enhanced usual care and (2) nurse-led prostate cancer survivorship essentials (PCEssentials) delivered over four tele-based sessions, with a booster session 5 months after session 1. Eligible participants are Australian men with prostate cancer commencing ADT and expected to be on ADT for a minimum of 12 months. Participants are followed up at 3, 6 and 12 months postrecruitment. Primary outcomes are HR-QoL and self-efficacy. Secondary outcomes are psychological distress, insomnia, fatigue and physical activity. A concurrent process evaluation with participants and study stakeholders will be undertaken to determine effectiveness of delivery of PCEssentials. ETHICS AND DISSEMINATION: Ethics approval was obtained from the Metro South Health HREC (HREC/2021/QMS/79429). All participants are required to provide written informed consent. Outcomes of this trial will be published in peer-reviewed journals. The findings will be presented at conferences and meetings, local hospital departments, participating organisations/clinical services, and university seminars, and communicated at community and consumer-led forums. TRIAL REGISTRATION NUMBER: ACTRN12622000025730.


Subject(s)
Cancer Survivors , Prostatic Neoplasms , Male , Humans , Prostatic Neoplasms/drug therapy , Prostatic Neoplasms/psychology , Quality of Life/psychology , Androgen Antagonists/therapeutic use , Androgens , Prostate , Survivorship , Nurse's Role , Australia , Randomized Controlled Trials as Topic
20.
JAMA Netw Open ; 7(3): e2356445, 2024 Mar 04.
Article in English | MEDLINE | ID: mdl-38441897

ABSTRACT

Importance: Despite higher atherosclerotic cardiovascular disease (ASCVD) risk, people with HIV (PWH) experience unique barriers to ASCVD prevention, such as changing models of HIV primary care. Objective: To test whether a multicomponent nurse-led strategy would improve systolic blood pressure (SBP) and non-high-density lipoprotein (HDL) cholesterol level in a diverse population of PWH receiving antiretroviral therapy (ART). Design, Setting, and Participants: This randomized clinical trial enrolled PWH at 3 academic HIV clinics in the US from September 2019 to January 2022 and conducted follow-up for 12 months until January 2023. Included patients were 18 years or older and had a confirmed HIV diagnosis, an HIV-1 viral load less than 200 copies/mL, and both hypertension and hypercholesterolemia. Participants were stratified by trial site and randomized 1:1 to either the multicomponent EXTRA-CVD (A Nurse-Led Intervention to Extend the HIV Treatment Cascade for Cardiovascular Disease Prevention) intervention group or the control group. Primary analyses were conducted according to the intention-to-treat principle. Intervention: The EXTRA-CVD group received home BP monitoring guidance and BP and cholesterol management from a dedicated prevention nurse at 4 in-person visits (baseline and 4, 8, and 12 months) and frequent telephone check-ins up to every 2 weeks as needed. The control group received general prevention education sessions from the prevention nurse at each of the 4 in-person visits. Main Outcomes and Measures: Study-measured SBP was the primary outcome, and non-HDL cholesterol level was the secondary outcome. Measurements were taken over 12 months and assessed by linear mixed models. Prespecified moderators tested were sex at birth, baseline ASCVD risk, and trial site. Results: A total of 297 PWH were randomized to the EXTRA-CVD arm (n = 149) or control arm (n = 148). Participants had a median (IQR) age of 59.0 (53.0-65.0) years and included 234 males (78.8%). Baseline mean (SD) SBP was 135.0 (18.8) mm Hg and non-HDL cholesterol level was 139.9 (44.6) mg/dL. At 12 months, participants in the EXTRA-CVD arm had a clinically significant 4.2-mm Hg (95% CI, 0.3-8.2 mm Hg; P = .04) lower SBP and 16.9-mg/dL (95% CI, 8.6-25.2 mg/dL; P < .001) lower non-HDL cholesterol level compared with participants in the control arm. There was a clinically meaningful but not statistically significant difference in SBP effect in females compared with males (11.8-mm Hg greater difference at 4 months, 9.6 mm Hg at 8 months, and 5.9 mm Hg at 12 months; overall joint test P = .06). Conclusions and Relevance: Results of this trial indicate that the EXTRA-CVD strategy effectively reduced BP and cholesterol level over 12 months and should inform future implementation of multifaceted ASCVD prevention programs for PWH. Trial Registration: ClinicalTrials.gov Identifier: NCT03643705.


Subject(s)
Atherosclerosis , Cardiovascular Diseases , Hypertension , Infant, Newborn , Female , Male , Humans , Middle Aged , Aged , Blood Pressure , Nurse's Role , Hypertension/drug therapy
SELECTION OF CITATIONS
SEARCH DETAIL
...